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이대목동병원 수면센터장 신경과, 수면센터 관심의료진 등록

전문 진료 분야

뇌전증, 경련성질환, 수면장애, 수면무호흡증, 뇌염/뇌수막염. 돌발성 운동유발 이상운동증, 실신, 하지불안증후군, 코로나 후 수면인지클리닉(금 오전)

진료 일정

진료예약 간편 예약 고맙습니다

학력 및 경력사항

학력사항

  • 의학박사 (고려대학교)
  • 의학석사 (이화여대)
  • 이화여대 의과대학 졸업

교육 및 연구경력

  • 2018-현재  | 이화메디테크 융합의료연구소장
  • 2012-현재  | 이대목동병원 수면센터장
  • 2010-2011  | 미국 예일대학교 신경과 교환교수
  • 2003-현재  | 이화여대 의과대학 신경과 교수
  • 2002-2003  | 미국 National Institutes of Health, NINDS Clinical Fellow
  • 2001-2002  | 미국 존스홉킨스의대 신경과 postdoctoral fellow
  • 2002-2003  | 미국 NINDS (National Instuties of Neurological Institutes and Stroke) clinical fellow
  • 2001-2002  | 존스홉킨스 의대 신경과 postdoctoral fellow
  • 2001  | 한국과학재단 박사후 해외연수과정 연구비 수상
  • 2000-2001  | 이대목동병원 신경과 임상강사
  • 1998-2000  | 삼성의료원 뇌전증/수면장애 전임의
  • 1993-1998  | 이대부속병원 수련의/신경과 전공의

수상경력

  • 2015 | 대한뇌기능매핑학회 학술연구상
  • 2009 | 대한뇌전증학회 우수연구상 수상
  • 2003 | 미국뇌전증학회 Milken Family postdoctoral research fellowship award 수상
  • 2003 | 미국 NINDS competitive intramural postdoctoral fellowship award 수상
  • 2001 | 대한여의사회 우수학술연구상 수상

기타 학술 관련 경력

  • 세계뇌전증협회 Task Force Member
  • 세계뇌기능매핑학회 Diversity & Gender Committee, Task Force Member
  • 미국뇌전증학회 정회원
  • 미국뇌신경과학회 정회원
  • 미국수면학회 정회원
  • 한국뇌기능매핑학회 학술이사
  • 대한수면학회 홍보이사
  • 대한뇌전증학회 편집위원장
  • 대한신경과학회 정회원

논문

  • Kim SH, Lee JW, Choi KG, Chung HW, Lee HW. 6-month longitudinal study of bone mineral density with antiepileptic drug monotherapy.  Epilepsy & Behavior . 2007;10:291-295. 
  • Choi BO, Hwang JH, Kim J, Cho EM, Cho SY, Hwang SJ, Lee HW, Kim SJ, Chung KW. A MELAS syndrome family harboring two mutations in mitochondrial genome.  Exp Mol Med. 2008;40(3):354-360. 
  • Kim JH, Lee HW, Cohen LG, Park KD, Choi KG. Motor cortical excitability in patients with Poststroke epilepsy.  Epilepsia. 2008;49(1): 117-124.. 
  • Lesser RP, Lee HW, Webber WR, Prince B, Crone NE, Miglioretti DL. Short-term variations in response distribution to cortical stimulation.  Brain. 2008;131(Pt 6): 1528-1539. 
  • Choi BO, Hwang JH, Kim J, Cho EM, Cho SY, Hwang SJ, Lee HW, Kim SJ, Chung KW. A MELAS syndrome family harboring two mutations in mitochondrial genome.  Exp Mol Med. 2008 Jun 30;40(3):354-360.. 
  • Lee HW, Shin JS, Webber WR, Crone NE, Gingis L, Lesser RP. Reorganization of corrtical motor and language distribution in human brain.  J Neurol Neurosurg Psychiatr . 2009; 80(3):285-290. 
  • Lee HW, Webber WR, Crone N, Miglioretti DL, Lesser RP. When is electrical cortical stimulation more likely to produce afterdischarges?.  Clin Neurophysiol. 2010 Jan;121(1):14-20. 
  • HELP Study Group. Multi-center study on migraine and seizure-related headache in patients with epilepsy.  Yonsei Med J. 2010 Mar;51(2):219-24. 
  • Kim GH, Lee HW, Park H, Lee SK, Lee SA, Kim YI, Song HK, Shin DJ, Hong SB. Seizure exacerbation and hormonal cycles in women with epilepsy.  Epilepsy Res. 2010 Aug;90(3):214-220. 
  • Lee SA, Lee HW, Heo K, Shin DJ, Song HK, Kim OJ, Lee SM, Kim SO, Lee BI. Cognitive and behavioral effects of lamotrigine and carbamazepine monotherapy in patients with newly diagnosed or untreated partial epilepsy.  Seizure. 2011 Jan;20(1):49-54. 
  • Yoo SS, Shim BS, Lee DH, Lee HW, Yoon H. Correlation between Nocturia and Sleep: A Questionnaire Based Analysis .  Korean J Urol. 2010 Nov;51(11):757-62. 
  • Kim HJ, Kim JH, Park KD, Choi KG, Lee HW. A survey of sleep deprivation patterns and their effects on cognitive functions of residents and interns in Korea.  Sleep Med. 2011 Apr;12(4):390-396. 
  • Heo K, Rhee Y, Lee HW, Lee SA, Shin DJ, Kim WJ, Song HK, Song K, Lee BI. The effect of topiramate monotherapy on bone mineral density and markers of bone and mineral metabolism in premenopausal women with epilepsy.  Epilepsia. 2011 Oct;52(10):1884-1889. 
  • Yang L, Shklyar I, Lee HW, Ezeani CC, Anaya J, Balakirsky S, Han X, Enamandram S, Men C, Cheng JY, Nunn A, Mayer T, Francois C, Albrecht M, Hutchison AL, Yap EL, Ing K, Didebulidze G, Xiao B, Hamid H, Farooque P, Detyniecki K, Giacino JT, Blumenfeld H. Impaired consciousness in epilepsy investigated by a prospective responsiveness in epilepsy scale (RES).  Epilepsia. 2012 Mar;53(3):437-447. 
  • Kim WS, Lee M, Han JM, Kim SE, Kim HJ, Kim BS, Kim BG, Lee HW. Acute and chronic effects of repeated 1 Hz rTMS on the temporal cortex.  Neuroreport. 2012 Jun 20;23(9):540-545. 
  • Youngblood MW, Han X, Farooque P, Jhun S, Bai X, Yoo JY, Lee HW, Blumenfeld H. Intracranial EEG surface renderings: new insights into normal and abnormal brain function.  Neuroscientist. 2013 Jun;19(3):238-247. 
  • Hyun JW, Chung HK, Kim SH, Choi YJ, Kim SJ, Kim HS, Lee HW. Two cases of chromosome 22q11.2 deletion syndrome diagnosed in 12-year-old boys with hypocalcemic seizures.  J Epilepsy Res. 2012 Dec 30;2:43-47. 
  • Cho YW, Hong SB, Kim DH, Lee HW, Joo EY, Kim JH, Shin WC, Park KH, Han SJ, Lee HW. The effect of ropinirole on the quality of life in patients with restless legs syndrome in Korea: an 8-week, multicenter, prospective study.  J Clin Neurol. 2013 Jan;9(1):51-56. 
  • Lee M, Kim SE, Kim WS, Lee J, Yoo HK, Park KD, Choi KG, Jeong SY, Kim BG, Lee HW. Interaction of motor training and intermittent theta burst stimulation in modulating motor cortical plasticity: influence of BDNF Val66Met polymorphism.  PLoS One. 2013;8(2):e57690. 
  • Lee M, Kim SE, Kim WS, Han J, Kim HJ, Kim BS, Kim JY, Hong SB, Kim BG, Lee HW. Cortico-cortical modulation induced by 1-Hz repetitive transcranial magnetic stimulation of the temporal cortex.  J Clin Neurol. 2013 Apr;9(2):75-82. 
  • Kim SE, Kim WS, Kim BG, Chung D, Jeong J, Lee JS, Tae WS, Hong SB, Lee HW. Spatiotemporal dynamics and functional correlates of evoked neural oscillations with different spectral powers in human visual cortex.  Clin Neurophysiol. 2013 Nov;124(11):2248-2256. 
  • Lee HW, Youngblood MW, Farooque P, Han X, Jhun S, Chen WC, Goncharova I, Vives K, Spencer DD, Zaveri H, Hirsch LJ, Blumenfeld H. Seizure localization using three-dimensional surface projections of intracranial EEG power.  Neuroimage. 2013 Dec;83:616-626. 
  • Kim DW, Lee SY, Chung SE, Cheong HK, Jung KY; Korean Epilepsy Society. Clinical characteristics of patients with treated epilepsy in Korea: a nationwide epidemiologic study.  Epilepsia. 2014 Jan;55(1):67-75. 
  • Koo DL, Hwang KJ, Han SW, Kim JY, Joo EY, Shin WC, Lee HW, Seo DW, Hong SB. Effect of oxcarbazepine on bone mineral density and biochemical markers of bone metabolism in patients with epilepsy.  Epilepsy Res. 2014 Mar;108(3):442-447. 
  • Kim SM, Song JY, Lee C, Lee HW, Kim JY, Hong SB, Jung KY. Effect of oxcarbazepine on background EEG activity and cognition in epilepsy.  J Epilepsy Res. 2013 Jun 30;3(1):7-15. 
  • Kim D, Seo JH, Joo EY, Lee HW, Shin WC, Hong SB. Cognitive and psychosocial effects of oxcarbazepine monotherapy in newly diagnosed partial epilepsy.  Clin Neuropharmacol. 2014 Jul-Aug;37(4):100-107. 
  • Lee HW, Arora J, Papademetris X, Tokoglu F, Negishi M, Scheinost D, Farooque P, Blumenfeld H, Spencer DD, Constable RT. Altered functional connectivity in seizure onset zones revealed by fMRI intrinsic connectivity.  Neurology. 2014 Dec 9;83(24):2269-2277. 
  • Lee JH, Kim SE, Park CH, Yoo JH, Lee HW. Gray and White Matter Volumes and Cognitive Dysfunction in Drug-Naïve Newly Diagnosed Pediatric Epilepsy.  Biomed Res Int. 2015;2015:923861. 
  • Lee SA, Kim MJ, Lee HW, Heo K, Shin DJ, Song HK, Kim OJ, Kim SO, Lee BI. The effect of recurrent seizures on cognitive, behavioral, and quality-of-life outcomes after 12 months of monotherapy in adults with newly diagnosed or previously untreated partial epilepsy.  Epilepsy Behav. 2015 Dec;53:202-208. 
  • Ahn S, Jun SB, Lee HW, Lee S. Computational modeling of epileptiform activities in medial temporal lobe epilepsy combined with in vitro experiments.  J Comput Neurosci. 2016 Oct;41(2):207-223. 
  • Choi HY, Kim SE, Lee HW, Kim EJ. Social Behavioral Problems and the Health-Related Quality of Life in Children and Adolescents with Epilepsy.  Psychiatry Investig. 2016 Sep;13(5):488-495. 
  • Kim HJ, Park KD, Choi KG, Lee HW. Clinical predictors of seizure recurrence after the first post-ischemic stroke seizure.  BMC Neurol . 2016;16(1):212. 
  • Lee M, Park CH, Chung HK, Kim HJ, Choi Y, Yoo JH, Yoon YC, Hong YB, Chung KW, Choi BO, Lee HW. Cerebral white matter abnormalities in patients with Charcot-Marie-Tooth disease.  Ann Neurol . 2017;81(1):147-151. 
  • Lee J, Song WJ, Lee HW, Shin HC. Novel Burst Suppression Segmentation in the Joint Time-Frequency Domain for EEG in Treatment of Status Epilepticus.  Comput Math Methods Med. 2016;2016:2684731. 
  • Ryu J, Lim KH, Ryu DR, Lee HW, Yun JY, Kim SW, Kim JH, Jung-Choi K, Kim H. Two cases of methyl alcohol intoxication by sub-chronic inhalation and dermal exposure during aluminum CNC cutting in a small-sized subcontracted factory..  Ann Occup Environ Med. 2016 Nov 15;28:65. . 
  • Choi JH, Lee SK, Gil YE, Ryu J, Jung-Choi K, Kim H, Choi JY, Park SA, Lee HW, Yun JY. Neurological Complications Resulting from Non-Oral Occupational Methanol Poisoning.  J Korean Med Sci . 2017;32(2):371-376. 
  • Song TJ, Park JH, Choi KH, Kim JH, Choi Y, Chang Y, Kim HJ, Moon J, Kim YJ, Lee HW. Is obstructive sleep apnea associated with the presence of intracranial cerebral atherosclerosis? .  Sleep Breath. 2017;21(3):639-646. 
  • Song TJ, Park JH, Choi KH, Chang Y, Moon J, Kim JH, Choi Y, Kim YJ, Lee HW. Moderate-to-severe obstructive sleep apnea is associated with cerebral small vessel disease.  Sleep Med. 2017;30:36-42. 
  • Kim JH, Lee SK, Loesch C, Namgoong K, Lee HW, Hong SB; Korean N01367 Study Group. Comparison of levetiracetam and oxcarbazepine monotherapy among Korean patients with newly diagnosed focal epilepsy: A long-term, randomized, open-label trial.  Epilepsia. 2017;58(4):e70-e74. 
  • Ahn S, Jo S, Jun SB, Lee HW, Lee S. Study on the mechanisms of seizure-like events suppression effect by electrical stimulation using a microelectrode array.  Neuroreport. 2017;28(9):471-478. 
  • Park CH, Choi YS, Jung AR, Chung HK, Kim HJ, Yoo JH, Lee HW. Seizure Control and Memory Impairment Are Related to Disrupted Brain Functional Integration in Temporal Lobe Epilepsy.  J Neuropsychiatry Clin Neurosci. 2017;29(4):343-350. 
  • Ahn S, Jo S, Jun SB, Lee HW, Lee S. Prediction of the Seizure Suppression Effect by Electrical Stimulation via a Computational Modeling Approach.  Front Comput Neurosci. 2017 May 29;11:39. 
  • Mula M, Cavalheiro E, Guekht A, Kanner AM, Lee HW, Özkara Ç, Thomson A, Wilson SJ. Educational needs of epileptologists regarding psychiatric comorbidities of the epilepsies: a descriptive quantitative survey.  Epileptic Disord. 2017;19(2):178-185. 
  • Lee J, Park J, Yang S, Kim H, Choi YS, Kim HJ, Lee HW, Lee BU. Early Seizure Detection by Applying Frequency-Based Algorithm Derived from the Principal Component Analysis.  Front Neuroinform. 2017;11:52. 
  • Hyun JW, Park JH, Kang BG, Park EY, Park B, Joo J, Kim JK, Kim SH, Jeong JH, Lee HW, Park KD, Choi KG, Hwang SH, Gwak HS, Kim HJ. Diagnostic and prognostic values of cerebrospinal fluid CYFRA 21-1 in patients with leptomeningeal carcinomatosis.  Oncotarget. 2017;8(32):53326-53335. 
  • Kim H, Choi Y, Joung HY, Choi YS, Kim HJ, Joo Y, Oh JH, Hann HJ, Cho ZH, Lee HW. Structural and Functional Alterations at Pre-Epileptic Stage Are Closely Associated with Epileptogenesis in Pilocarpine-induced Epilepsy Model.  Exp Neurobiol. 2017 Oct;26(5):287-294. 
  • Lee BI, No SK, Yi SD, Lee HW, Kim OJ, Kim SH, Kim MK, Kim SE, Kim YS, Kim JM, Lee SJ, Shin DJ, Park SP, Kim YI, Heo K, Cho YW, Cho YJ, Kim YN. Unblinded, randomized multicenter trial comparing lamotrigine and valproate combination with controlled-release carbamazepine monotherapy as initial drug regimen in untreated epilepsy.  Seizure. 2018;55:17-24. 
  • Kim HJ, Lee JH, Park CH, Hong HS, Choi YS, Yoo JH, Lee HW. Role of Language-Related Functional Connectivity in Patients with Benign Childhood Epilepsy with Centrotemporal Spikes.  J Clin Neurol. 2018;14:48-57. 
  • Moon J, Choi KH, Park JH, Song TJ, Choi YS, Kim JH, Kim HJ, Lee HW. Sympathetic Overactivity Based on Heart-Rate Variability in Patients with Obstructive Sleep Apnea and Cerebral Small Vessel Disease.  J Clin Neurol. 2018;14:310-319. 
  • Park CH, Choi YS, Kim HJ, Chung HK, Jung AR, Yoo JH, Lee HW. Interactive effects of seizure frequency and lateralization on intratemporal effective connectivity in temporal lobe epilepsy.  Epilepsia. 2018; 59(1): 215-225. 
  •  Radiomics features of hippocampal regions in magnetic resonance imaging can differentiate medial temporal lobe epilepsy patients from healthy controls.  SCIENTIFIC REPORTS. 2020, v.10 no.1, 19567. 
  •  Sex differences in deterioration of sleep properties associated with aging: A 12-year longitudinal cohort study.  Journal of Clinical Sleep Medicine. 2021, v.17 no.5, 964-972. 
  •  A longitudinal observational population-based study of brain volume associated with changes in sleep timing from middle to late-life.  Sleep. 2021, v.44 no.4, 0.