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진료과
외과(유방암ㆍ갑상선암센터)
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이대여성암병원장 외과(유방암ㆍ갑상선암센터), 유방암센터 관심의료진 등록

전문 진료 분야

유방암, 갑상선암

진료 일정

진료예약 간편 예약 고맙습니다

학력 및 경력사항

학력사항

  • 서울대학교 대학원 의학박사
  • 서울대학교 대학원 의학석사
  • 서울대학교 의과대학 졸업

교육 및 연구경력

  • 2018-2020  | 이화여자대학교 의무부총장 겸 의료원장
  • 2009-2018  | 이대여성암병원 유방암·갑상선암센터장
  • 2007  | International Executive Meeting in MGH
  • 2005-2006  | UCLA/Revlon breast Cancer Center & Gonda Breast cancer Research Laboratory 연수
  • 2001-현재  | 이화여자대학교 의과대학 외과 교수
  • 1997-2001  | 이화여자대학교 의과대학 외과 조교수
  • 1993-1997  | 지방공사 강남병원(현 서울의료원) 외과 과장
  • 1989-1993  | 서울대학교병원 외과 레지던트
  • 1988-1989  | 서울대학교병원 인턴

수상경력

  • 1996 | 최우수 박사학위 논문상 수상
  • 2004 | 대한암학회 GSK 학술상 수상
  • 2009 | 한국유방암학회 동아학술상 수상
  • 2014 | 대한내분비내과학회 명민학술상 수상

기타 학술 관련 경력

  • 2018-현재  | 사립대의료원협의회 총무이사
  • 2018-현재  | 대한병원협회 상임이사
  • 대한갑상선-내분비외과학회 평생회원, 상임이사(의료심사), 세부전문의위원회 위원장, 부회장
  • 한국유방암학회 평생회원, 상임이사(홍보위원장), 법제이사, 부회장 역임
  • 대한외과학회 정회원, 교육위원, 세부전문의 분과 TFT 위원, 대한 외과학회지 심사위원 역임
  • 대한암학회 정회원
  • 대한내시경복강경외과학회 정회원
  • 임상종양학회 평생회원

논문

  •  Effect of radiotherapy sequence on long-term outcome in patients with node-positive breast cancer: a retrospective study.  Scientific Reports. 2022, v.12 no.1, 10729. 
  •  Number of Tumor Foci as a Risk Factor for Recurrence in Papillary Thyroid Carcinoma: Does It Improve Predictability?.  Cancers. 2022, v.14 no.17, 4141. 
  •  Predictors of Recurrence in Patients with Papillary Thyroid Carcinoma: Does Male Sex Matter?.  Cancers. 2022, v.14 no.8, 1896. 
  •  Staphylococcus aureus-Derived Extracellular Vesicles Enhance the Efficacy of Endocrine Therapy in Breast Cancer Cells.  Journal of Clinical Medicine. 2022, v.11 no.7, 2030. 
  •  Treatment Outcomes according to the EndoPredict Score in ER-Positive, HER2-Negative Early Breast Cancer.  Breast Care. 2022, v.17 no.6, 561-566. 
  •  Association of Multifocality with Prognosis of Papillary Thyroid Carcinoma: A Systematic Review and Meta-analysis.  JAMA Otolaryngology - Head and Neck Surgery. 2021, v.147 no.10, 847-854. 
  •  Bacterial extracellular vesicles affect endocrine therapy in MCF7 cells.  Medicine. 2021, v.100 no.18, e25835. 
  •  Clinical Outcomes Following Letrozole Treatment according to Estrogen Receptor Expression in Postmenopausal Women: LETTER Study (KBCSG-006).  JOURNAL OF BREAST CANCER. 2021, v.24 no.2, 164-174. 
  •  Selenium inhibits growth of trastuzumab-resistant human breast cancer cells via downregulation of Akt and beclin-1.  PLOS ONE. 2021, v.16 no.9, e0257298. 
  •  The comparison of breast reconstruction using two types of acellular dermal matrix after breast-conserving surgery.  Journal of Clinical Medicine. 2021, v.10 no.15, 3430. 
  •  A nationwide, multicenter retrospective study on the effectiveness and safety of eribulin in Korean breast cancer patients (REMARK).  Breast. 2020, v.54, 121-126. 
  •  Adding Ovarian Suppression to Tamoxifen for Premenopausal Breast Cancer: A Randomized Phase III Trial.  JOURNAL OF CLINICAL ONCOLOGY. 2020, v.38 no.5. 
  •  BRCA1/BRCA2 Pathogenic Variant Breast Cancer: Treatment and Prevention Strategies.  Annals of laboratory medicine. 2020, v.40 no.2, 114-121. 
  •  Efficacy of health coaching and a web-based program on physical activity, weight, and distress management among cancer survivors: A multi-centered randomised controlled trial.  Psycho-Oncology. 2020, v.29 no.7, 1105-1114. 
  •  Prognosis of papillary thyroid cancer in patients with Graves’ disease: a propensity score-matched analysis.  World Journal of Surgical Oncology. 2020, v.18 no.1, 266. 
  •  Serum Levels and Glycosylation Changes of Alpha-1-Acid Glycoprotein According to Severity of Breast Cancer in Korean Women.  JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY. 2020, v.30 no.9, 1297-1304. 
  •  Sodium Selenite Enhanced the Anti-proliferative Effect of MEK-ERK Inhibitor in Thyroid Cancer Cells.  IN VIVO. 2020, v.34 no.1, 185-190. 
  •  Circulating Plasmacytoid and Myeloid Dendritic Cells in Breast Cancer Patients: A Pilot Study.  JOURNAL OF BREAST CANCER. 2019, v.22 no.1, 29-37. 
  •  Clinical subtypes and prognosis in breast cancer according to parity: a nationwide study in Korean Breast Cancer Society.  BREAST CANCER RESEARCH AND TREATMENT. 2019, v.173 no.3, 679-691. 
  •  Correction: 33rd Annual meeting & pre-conference programs of the Society for Immunotherapy of Cancer (SITC 2018) (Journal for ImmunoTherapy of Cancer (2018) 6:Suppl 1 DOI: 10.1186/s40425-018-0422-y).  Journal for ImmunoTherapy of Cancer. 2019, v.7 no.1, 46. 
  •  Human Epidermal Growth Factor Receptor 2-Subtype Invasive Ductal Carcinoma Recurring as Basal-Human Epidermal Growth Factor Receptor 2-Subtype Squamous Cell Carcinoma.  JOURNAL OF BREAST CANCER. 2019, v.22 no.3, 484-490. 
  •  Increased risk of postoperative complications after total thyroidectomy with Graves' disease.  Head and Neck. 2019, v.41 no.2, 281-285. 
  •  Physiologic intestinal F-18-FDG uptake is associated with alteration of gut microbiota and proinflammatory cytokine levels in breast cancer.  SCIENTIFIC REPORTS. 2019, v.9, 18273. 
  •  Quantitative Assessment of the Learning Curve for Robotic Thyroid Surgery.  JOURNAL OF CLINICAL MEDICINE. 2019, v.8 no.3, 402. 
  •  Reinterpretation of BRCA1 and BRCA2 variants of uncertain significance in patients with hereditary breast/ovarian cancer using the ACMG/AMP 2015 guidelines.  Breast Cancer. 2019, v.26 no.4, 510-519. 
  •  Routine low-dose calcium supplementation after thyroidectomy does not reduce the rate of symptomatic hypocalcemia: A prospective randomized trial .  Annals of Surgical Treatment and Research. 2019, v.96 no.4, 177-184. 
  •  Efficacy of a clinical pathway for patients with thyroid cancer.  JOURNAL OF THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK. Volume 40, Issue 9. 
  •  Use of CA15-3 for screening breast cancer: An antibody-lectin sandwich assay for detecting glycosylation of CA15-3 in sera.  ONCOLOGY REPORTS. Volume 40 Issue 1. 
  •  Feasibility of Classification of Triple Negative Breast Cancer by Immunohistochemical Surrogate Markers.  Clinical Breast Cancer. Volume 18, Issue 5, October 2018, Pages e1123-e1132. 
  •  The effect of adjuvant chemotherapy on survival in Korean patients with node negative T1c, triple negative breast cancer.  PLOS Computational Biology Published. May 16, 2018. 
  •  Dystrophic Calcifications in the Breast from Secondary Hyperparathyroidism.  Breast Care/Multidisciplinary Journal for Research, Diagnosis and Therapy Breast Care. 2018;13:44-46. 
  •  Assessment of Quality of Life and Safety in Postmenopausal Breast Cancer Patients Receiving Letrozole as an Early Adjuvant Treatment.  Journal of Breast Cancer. v.21(2); Jun 2018. 
  •  Percentage Decline of Parathyroid Hormone Level is a Predictor for Post-thyroidectomy Symptomatic Hypocalcemia.  Journal of Breast Cancer. v.17(4); Dec 2017. 
  •  Reproductive factors as risk modifiers of breast cancer in BRCA mutation carriers and high-risk non-carriers.  Oncotarget. 2017 Nov 24; 8(60): 102110–102118. 
  •  Endoscopic Thyroidectomy Via the Cervico-axillary Approach for Thyroid Cancer: Initial Experience in a Single Institute.  Korean Journal of Endocrine Surgery. v.17(1); Mar 2017. 
  •  Suppression of Lipopolysaccharide-Induced Neuroinflammation by Morin via MAPK, PI3K/Akt, and PKA/HO-1 Signaling Pathway Modulation.  Journal of Agricultural and Food Chemistry. 2017, 65, 2, 373-382. 
  •  Lab on a fabric: Mass producible and low-cost fabric filters for the high throughput viable isolation of circulating tumor cells.  Biosensors and Bioelectronics. Volume 91, 15 May 2017, Pages 747-755. 
  •  Strong Correlation of Indoleamine 2,3-Dioxygenase 1 Expression with Basal-Like Phenotype and Increased Lymphocytic Infiltration in Triple-Negative Breast Cancer.  Journal of Cancer. 2017; 8(1): 124–130. 
  •  Attenuation of collagen-induced arthritis by hyperbaric oxygen therapy through altering immune balance in favor of regulatory T cells.  Journal of the Undersea and Hyperbaric Medical Society, Inc. 01 Jul 2017, 44(4):321-330. 
  •  High-purity capture and release of circulating exosomes using an exosome-specific dual-patterned immunofiltration (ExoDIF) device.  Nanoscale. Issue 36, 2017. 
  •  Clinicopathologic Characteristics of Pregnancy-Associated Breast Cancer: Results of Analysis of a Nationwide Breast Cancer Registry Database.  Journal of Breast Cancer. v.20(3); Sep 2017. 
  •  The Effect of Reproductive Factors on Breast Cancer Presentation in Women Who Are BRCA Mutation Carrier.  Journal of Breast Cancer. v.20(3); Sep 2017. 
  •  Dual-patterned immunofiltration (DIF) device for the rapid efficient negative selection of heterogeneous circulating tumor cells.  Lab on a Chip. Issue 24, 2016. 
  •  Cytokeratin 18 is necessary for initiation of TGF-beta 1-induced epithelial-mesenchymal transition in breast epithelial cells.  Molecular and Cellular Biochemistry. December 2016, Volume 423, Issue 1–2, pp 21–28|. 
  •  Age-related reduction of antibody response against the human endogenous retrovirus K envelope in women.  Oncotarget. v.7(14); 2016 Apr 5. 
  •  Exogenous C2 Ceramide Suppresses Matrix Metalloproteinase Gene Expression by Inhibiting ROS Production and MAPK Signaling Pathways in PMA-Stimulated Human Astroglioma Cells.  International Journal of Molecular Sciences. 2016, 17(4), 477. 
  •  Expression patterns of GATA3 and the androgen receptor are strongly correlated in patients with triple-negative breast cancer.  Human Pathology. Volume 55, September 2016, Pages 190-195. 
  •  The role of the addition of ovarian suppression to tamoxifen in young women with hormone-sensitive breast cancer who remain premenopausal or regain menstruation after chemotherapy (ASTRRA): study protocol for a randomized controlled trial and progress.  BMC Cancer. 201616:319. 
  •  Syndecan-2 enhances E-cadherin shedding and fibroblast-like morphological changes by inducing MMP-7 expression in colon cancer cells.  Biochemical and Biophysical Research Communications. Volume 477, Issue 1, 12 August 2016, Pages 47-53. 
  •  A lectin-based approach to detecting carcinogenesis in breast tissue.  Oncology Letters. April 18, 2016 Pages: 3889-3895. 
  •  Two-year Follow-up of Volumetric-modulated Arc Therapy for Treating Internal Mammary Nodes in Locally Advanced Breast Cancer.  Intermational Journal of Cancer Research and Treatment /Anticancer Research. September 2016 vol. 36 no. 9 4847-4851. 
  •  The value of cytoplasmic Y-box-binding protein 1 as a prognostic marker for breast cancer in Korean.  Breast Cancer. September 2016, Volume 23, Issue 5, pp 685–691. 
  •  Extracellular vesicle derived from Staphylococcus aureus enhanced tamoxifen effect in ER-positive breast cancer cells.  Journal of Breast Cancer.  
  •  Second Primary Thyroid Cancer in Breast Cancer Survivors: An Institutional Review of 20-Year Experience.  Journal of Breast Cancer.  
  •  Diagnosis of breast cancer using blood and urine microbiome.  Annual Congress of KSS 2018 70th Congress of the Korean Surgical Society. 2018.11, 377-378 (2 pages). 
  •  Microbiomes affect the therapeutic resistance of HER2 type breast cancer.  Annual Congress of KSS 2018 70th Congress of the Korean Surgical Society. 2018.11, 320-321 (2 pages). 
  •  The Diagnostic algorithm of breast cancer using the human microbiome.  Annual Congress of KSS 2018 70th Congress of the Korean Surgical Society. 2018.11, 377-378 (2 pages). 
  •  Novel Pharmacobiotic approach to enhance the tamoxifen efficacy using bacterial extracellular vesicles as the immunotherapy in breast cancer.  Annual Congress of KSS 2018 70th Congress of the Korean Surgical Society.  
  •  The effect of symbiotic gut bacterial differences in young breast cancer patients.  Noplasia. October 2018Volume 41, Supplement 1, Pages S18–S19. 
  •  Diagnostic significance of breast cancer subtypes via bacterial extracellular vesicles in urine .  Journal of Breast Cancer.  
  •  The effect of bacterial extracellular vesicles from Staphylococcus aureus and Klebsiella pneumoniae for growth on breast cancer cell lines.  Journal of Breast Cancer.  
  •  Microbial nanovesicles of urine as a diagnostic tool of breast cancer.  Journal of Breast Cancer.  
  •  Graves' disease does not affect the prognosis of papillary throid cancer.  Annual Congress of KSS 2017 69th Congress of the Korean Surgical Society.  
  •  Diagnosis of breast cancer via 16S rDNA sequencing of microbial nanovesicles in blood or urine.  Annual Congress of KSS 2017 69th Congress of the Korean Surgical Society.  
  •  Evaluation of breast edema in early breast cancer patients after breast conserving surgery: a pilot study.  Journal of Breast Cancer.  
  •  The Utility of Scalp cooling syatem for prevention of hair loss and scalp follicutitis in breast cancer patients receiving chemotherapy: a prospective cohort study.  Journal of Breast Cancer.  
  •  Clincopathologic predictive factors of Endopredict high risk group in breast cancer.  Annual Congress of KSS 2016 68th Congress of the Korean Surgical Society.  
  •  Tract Recurrence of a Follicular Neoplasm after Endoscopic thyroidectomy.  Patients with Remarkable Features or Rare Disorders. Thyroid, Vol. 22, No. 2. 
  •  Accuracy of intraoperative touch imprint cytology of breast lesions using core-needle biopsy specimen: A comparision with frozen section diagnosis.  VIRCHOWS ARCHIV. vol. 469, pp. S96 - S96. 
  •  Expression pattern of GATA3 and androgen receptor are strongly correlated in patients with triple negative breast cancer.  Human Pathology. Volume 55, September 2016, Pages 190-195. 
  •  내분비외과학 2nd Edition.    
  •  제4판 유방학.    
  •  바실러스 속 세균 유래 세포밖 소포체를 포함하는 임신관련 질환 치료용 조성물.