학력 및 경력사항

• 연세대학교 의과대학 보건대학원 석사학위 취득
• 이화여자대학교 대학원 박사학위 취득
• 이화여자대학교 대학원 의학과 석사과정 졸업
• 이화여자대학교 의과대학 의학과 졸업

• 2023-현재  | 이화의료원 이화의생명연구원장
• 2021-2022  | 이대목동병원 의료기술협력단장
• 2019-2020  | 이대목동병원 융합연구원장
• 2018-현재  | 한국 연구재단 기초연구본부 의약학단 전문위원
• 2018-현재  | 대한민국 의학한림원 정회원
• 2017-현재  | 과학기술 총연합회 이사
• 2017-2019  | 세계 PREBIC(Preterm birth international collaborative) board member
• 2017-2021  | 이화의대 산부인과학교실 주임교수
• 2016-2018  | 이대목동병원 산부인과 과장
• 2013-2015  | 이화의료원 부속 목동병원 교육연구부장
• 2011-2013  | 보건산업진흥원 PM제도 운영위원
• 2007-현재  | 이화의대 교수
• 2002-2013  | 이대부속목동병원 모자센터 소장
• 1997-2002  | 이화여자대학교 의과대학 산부인과 조교수
• 1993-1994  | 이화여자대학교 의료원 부속병원 산부인과 전임의
• 1989-1993  | 이화여자대학교 의료원 부속병원 산부인과 레지던트 과정 수료

• 2022-현재  | 대한모체태아의학회 회장
• 2023-현재  | 한국모유수유넷 회장
• 2018-2021  | 대한모체태아의학회 부회장
• 2017-현재  | 대한산부인과 학회 상임이사
• 2016-2018  | 모체태아의학회 정책위원장
• 2016-2018  | 대한모자보건학회 기획법제위원장
• 2012-2014  | 대한의학유전학회 학술위원
• 2012-2013  | 이산회 학술이사
• 2011-2021  | 조산연구회 회장
• 2010-2016  | 모체태아의학회 간행위원장
• 2009-현재  | 대한산부인과학회 심사위원
• 2007-2012  | 대한산부인과학회 편집위원
• 2004-2010  | 대한산부인과 초음파학회 이사
• 2002-2004  | 주산 의학회 기획위원
• 2002-2008  | 태아 의학회 학술위원
• 1998-현재  | 태아의학회 위원

•  Prenatal bisphenol A and birth outcomes : MOCEH (Mothers and Children's Environmental Health) study.  INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH. 2014, v.217 no.2-3, 328-334. 
•  Postnatal growth following prenatal lead exposure and calcium intake.  Pediatrics. 2014, v.134 no.6, 1151-1159. 
•  Increased Frequency of Aneuploidy in Long-Lived Spermatozoa.  PLOS ONE. 2014, v.9 no.12. 
•  Effects of β2-adrenergic receptor gene polymorphisms on ritodrine therapy in pregnant women with preterm labor: Prospective follow-up study.  International Journal of Molecular Sciences. 2014, v.15 no.7, 12885-12894. 
•  Effects of Single-Nucleotide Polymorphisms of FMO3 and FMO6 Genes on Pharmacokinetic Characteristics of Sulindac Sulfide in Premature Labor.  DRUG METABOLISM AND DISPOSITION. 2014, v.42 no.1, 40-43. 
•  Can Proopiomelanocortin Methylation Be Used as an Early Predictor of Metabolic Syndrome?.  DIABETES CARE. 2014, v.37 no.3, 734-739. 
•  Association of mid-pregnancy antioxidative vitamin and oxidative stress levels with infant growth during the first 3 years of life.  FOOD & NUTRITION RESEARCH. 2014, v.58. 
•  The preventive effect of breast-feeding for longer than 6 months on early pubertal development among children aged 7-9 years in Korea.  Public Health Nutrition. 2015, v.18 no.18, 3300-3307. 
•  The Compositional Difference of Bacteria-Derived Extracellular Vesicles in Urine Between Women With and Without Pregnancy Based on Metagenomic Analysis.  REPRODUCTIVE SCIENCES. 2015, v.22, 279A-280A. 
•  Relationship of serum 25-Hydroxyvitamin D (25[OH]D) levels and components of metabolic syndrome in prepubertal children.  Nutrition. 2015, v.31 no.42320, 1324-1327. 
•  Proteomic analysis of one-carbon metabolismrelated marker in liver of rat offspring.  Molecular and Cellular Proteomics. 2015, v.14 no.11, 2901-2909. 
•  Proteomic analysis of fetal programming-related obesity markers.  Proteomics. 2015, v.15 no.15, 2669-267. 
•  Effect of maternal excessive sodium intake on postnatal brain development in rat offspring.  NUTRITIONAL NEUROSCIENCE. 2015, v.18 no.3, 118-124. 
•  Comparative Analysis of Midtrimester Amniotic Fluid Cytokine Levels to Predict Spontaneous Very Pre-term Birth in Patients with Cervical Insufficiency.  American Journal of Reproductive Immunology. 2015, 21 NOV 2015. 
•  Screening for chromosomal abnormalities using combined test in the first trimester of pregnancy.  Obstetrics & Gynecology Science. 2016, v.59 no.5, 357~366. 
•  Progesterone treatment for the prevention of preterm birth.  JOURNAL OF THE KOREAN MEDICAL ASSOCIATION. 2016, v.59 no.4, 319-325. 
•  Prenatal exposure to perfluorinated compounds affects thyroid hormone levels in newborn girls.  ENVIRONMENT INTERNATIONAL. 2016, v.94, 607-613. 
•  Prenatal Exposure to Perfluorinated Compounds Affects Birth Weight Through GSTM1 Polymorphism.  JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE. 2016, v.58 no.6, E198-E205. 
•  Neurodevelopment in early childhood affected by prenatal lead exposure and iron intake.  Medicine (United States). 2016, v.95 no.4. 
•  Maternal food restriction during pregnancy and lactation adversely affect hepatic growth and lipid metabolism in three-week-old rat offspring.  International Journal of Molecular Sciences. 2016, v.17 no.12. 
•  Maternal food restriction during pregnancy and lactation adversely affect hepatic growth and lipid metabolism in three-week-old rat offspring.  International Journal of Molecular Sciences. 2016, v.17 no.12. 
•  Long working hours and overweight and obesity in working adults.  Annals of Occupational and Environmental Medicine. 2016, v.28 no.3, 1~9. 
•  DNA methylations of MC4R and HNF4 are associated with increased triglyceride levels in cord blood of preterm infants.  MEDICINE. 2016, v.95 no.35. 
•  DNA Methylation of the Proopiomelanocortin Gene in Overweight and Obese Children as a Biomarker to Predict Metabolic Syndrome.  REPRODUCTIVE SCIENCES. 2016, v.23, 231A-231A. 
•  Comparison of subfoveal choroidal thickness in healthy pregnancy and pre-eclampsia.  EYE. 2016, v.30 no.3, 349-354. 
•  Combined effect of folate and adiposity on homocysteine in children at three years of age.  NUTRITION RESEARCH AND PRACTICE. 2016, v.10 no.1, 74-80. 
•  A Comparative Analysis of Microarray-Based DNA Methylation in Maternal Blood and Amnion.  REPRODUCTIVE SCIENCES. 2016, v.23, 146A-146A. 
•  16S rRNA gene-based metagenomic analysis reveals differences in bacteria-derived extracellular vesicles in the urine of pregnant and non-pregnant women.  EXPERIMENTAL AND MOLECULAR MEDICINE. 2016, v.48. 
•  What is fetal programming?: A lifetime health is under the control of in utero health.  Obstetrics and Gynecology Science. 2017, v.60 no.6, 506-519. 
•  The effect of prenatal TVOC exposure on birth and infantile weight: The Mothers and Children's Environmental Health study.  Pediatric Research. 2017, v.82 no.3, 423-428. 
•  The Vaginal Microbiota Composition at First Admission in Korean Pregnancy Women.  REPRODUCTIVE SCIENCES. 2017, v.24, 173A-173A. 
•  Sex chromosome-dependent differential viability of human spermatozoa during prolonged incubation.  Human Reproduction. 2017, v.32 no.6, 1183-1191. 
•  Path analysis of prenatal mercury levels and birth weights in Korean and Taiwanese birth cohorts.  Science of the Total Environment. 2017, v.605-606, 1003-1010. 
•  POMC, MC4R and HNF4A Methylation Are Associated with Metabolic Components in Obese Children.  REPRODUCTIVE SCIENCES. 2017, v.24, 259A-259A. 
•  Effects of Adrenal Androgen Levels on Bone Age Advancement in Prepubertal Children: Using the Ewha Birth and Growth Cohort Study.  JOURNAL OF KOREAN MEDICAL SCIENCE. 2017, v.32 no.6, 968-973. 
•  Effects of Adrenal Androgen Levels on Bone Age Advancement in Prepubertal Children: Using the Ewha Birth and Growth Cohort Study.  JOURNAL OF KOREAN MEDICAL SCIENCE. 2017, v.32 no.6, 968-973. 
•  Association of gestational weight gain with maternal and infant outcomes: A systematic review and meta-analysis.  JAMA - Journal of the American Medical Association. 2017, v.317 no.21, 2207-2225. 
•  Association of Vac A- and Cag A-specific Helicobacter pylori strain infection with spontaneous preterm birth.  JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE. 2017, v.30 no.8, 995-1000. 
•  Association between ß2-adrenergic receptor gene polymorphisms and adverse events of ritodrine in the treatment of preterm labor: A prospective observational study.  BMC Genetics. 2017, v.18 no.1. 
•  Association between CACNA1C gene polymorphisms and ritodrine-induced adverse events in preterm labor patients.  EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2017, v.73 no.7, 837-842. 
•  Gestational weight gain across continents and ethnicity: systematic review and meta-analysis of maternal and infant outcomes in more than one million women.  BMC MEDICINE. 2018, v.16, 153. 
•  Efficacy and safety of ferric carboxymaltose versus ferrous sulfate for iron deficiency anemia during pregnancy: subgroup analysis of Korean women.  BMC PREGNANCY AND CHILDBIRTH. 2018, v.18, 349. 
•  Differential expression and methylation of integrin subunit alpha 11 and thrombospondin in the amnion of preterm birth.  Obstetrics and Gynecology Science. 2018, v.61 no.5, 565-574. 
•  Deleterious genetic variants in ciliopathy genes increase risk of ritodrine-induced cardiac and pulmonary side effects.  BMC MEDICAL GENOMICS. 2018, v.11. 
•  Association between the DNA methylations of POMC, MC4R, and HNF4A and metabolic profiles in the blood of children aged 7-9 years.  BMC PEDIATRICS. 2018, v.18. 
•  Vaginal microbiome profiles of pregnant women in Korea using a 16S metagenomics approach.  AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2019, v.82 no.1, e13124. 
•  he Protective Effect of Exclusive Breastfeeding on Overweight/Obesity in Children with High Birth Weight.  JOURNAL OF KOREAN MEDICAL SCIENCE. 2019, v.34 no.10, UNSP e85. 
•  Preterm birth rate and dilemma of preterm labor treatment in Asia.  PLACENTA. 2019, v.79, 68-71. 
•  Pathogenetic factors involved in recurrent pregnancy loss from multiple aspects.  Obstetrics and Gynecology Science. 2019, v.62 no.4, 212-223. 
•  MC4R and HNF4α promoter methylation at birth contribute to triglyceride levels in childhood: A prospective cohort study.  Medicine. 2019, v.98 no.28, e16424. 
•  Effects of PDE4 gene polymorphisms on efficacy and adverse drug events of ritodrine therapy in preterm labor patients: a prospective observational study.  EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2019, v.75 no.10, 1379-1386. 
•  Blood Microbial Communities During Pregnancy Are Associated With Preterm Birth.  FRONTIERS IN MICROBIOLOGY. 2019, v.10, 1122. 
•  낙태법 개정 관련 의료적 이슈와 산부인과의 입장.  한국모자보건학회지. 2020, v.24 no.1, 9-17. 
•  Vaginal compared with intramuscular progestogen for preventing preterm birth in high-risk pregnant women (VICTORIA study): a multicentre, open-label randomised trial and meta-analysis.  BJOG: An International Journal of Obstetrics and Gynaecology. 2020, v.127 no.13, 1646-1654. 
•  The Clinical Usefulness of Predictive Models for Preterm Birth with Potential Benefits: A KOrean Preterm collaboratE Network (KOPEN) Registry-Linked Data-Based Cohort Study.  INTERNATIONAL JOURNAL OF MEDICAL SCIENCES. 2020, v.17 no.1, 1-12. 
•  Population Pharmacokinetics of Sulindac and Genetic Polymorphisms of FMO3 and AOX1 in Women with Preterm Labor.  Pharmaceutical Research. 2020, v.37 no.3, 44. 
•  Maternal Malnutrition Affects Hepatic Metabolism through Decreased Hepatic Taurine Levels and Changes in HNF4A Methylation.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2020, v.21 no.23, 9060. 
•  Longitudinal association between environmental tobacco smoke exposure and behavioral problems in children from ages 5 to 9.  Science of the Total Environment. 2020, v.746, 141327. 
•  Long-term effects of pro-opiomelanocortin methylation induced in food-restricted dams on metabolic phenotypes in male rat offspring.  Obstetrics and Gynecology Science. 2020, v.63 no.3, 239-250. 
•  Influence of GRK5 gene polymorphisms on ritodrine efficacy and adverse drug events in preterm labor treatment.  Scientific Reports. 2020, v.10 no.1, 1351. 
•  Identifying genetic variants associated with ritodrine-induced pulmonary edema.  PLOS ONE. 2020, v.15 no.11, e0241215. 
•  Identification of Potential Biomarkers in the Cervicovaginal Fluid by Metabolic Profiling for Preterm Birth.  METABOLITES. 2020, v.10 no.9, 349. 
•  Hospitalizations and mortality among patients with fetal alcohol spectrum disorders: a prospective study.  SCIENTIFIC REPORTS. 2020, v.10 no.1, 19512. 
•  ffects ofKCNMB2gene polymorphisms on ritodrine therapy outcomes in women with preterm labor.  PHARMACOGENETICS AND GENOMICS. 2020, v.30 no.6, 124-130. 
•  Association between pre-and postnatal growth and longitudinal trends in serum uric acid levels and blood pressure in children aged 3 to 7 years.  BMC Pediatrics. 2020, v.20 no.1, 23. 
•  Alcohol Use Disorders and Increased Risk of Adverse Birth Complications and Outcomes: An 11-Year Nationwide Cohort Study.  INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. 2020, v.17 no.22, 8515. 
•  Vaginal health in women and the possibility of predicting preterm birth through microbiome analysis.  Journal of the Korean Medical Association. 2021, v.64 no.12, 833-840. 
•  The combined effects of fine particulate matter and temperature on preterm birth in Seoul, 2010–2016.  International Journal of Environmental Research and Public Health. 2021, v.18 no.4, 1-8. 
•  Prenatal Exposure to Alcohol, Tobacco, and Coffee: Associated Congenital Complications and Adverse Birth Outcomes.  INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. 2021, v.18 no.6, 3140. 
•  Molecular mechanism of microbiota metabolites in preterm birth: Pathological and therapeutic insights.  International Journal of Molecular Sciences. 2021, v.22 no.15, 8145. 
•  Integrative analysis of transcriptomic data for identification of T-cell activation-related mRNA signatures indicative of preterm birth.  Scientific Reports. 2021, v.11 no.1, 2392. 
•  Identification of Indicators for Preterm Birth Using Retinoid Metabolites.  METABOLITES. 2021, v.11 no.7, 443. 
•  Endocrine-disrupting chemicals and infectious diseases: From endocrine disruption to immunosuppression.  International Journal of Molecular Sciences. 2021, v.22 no.8, 3939. 
•  Elevated methylation of the vault RNA2-1 promoter in maternal blood is associated with preterm birth.  BMC GENOMICS. 2021, v.22 no.1, 528. 
•  Cohort profile: the Ewha Birth and Growth Study.  EPIDEMIOLOGY AND HEALTH. 2021, v.43, e2021016. 
•  Association between ADCY9 Gene Polymorphisms and Ritodrine Treatment Outcomes in Patients with Preterm Labor.  PHARMACEUTICS. 2021, v.13 no.10, 1653. 
•  Ureaplasma and Prevotella colonization with Lactobacillus abundance during pregnancy facilitates term birth.  Scientific Reports. 2022, v.12 no.1, 22303. 
•  Predicting preterm birth through vaginal microbiota, cervical length, and WBC using a machine learning model.  FRONTIERS IN MICROBIOLOGY. 2022, v.13, 912853. 
•  Development of a New Biomarker Model for Predicting Preterm Birth in Cervicovaginal Fluid.  METABOLITES. 2022, v.12 no.8, 734. 
•  Associations of GNAS and RGS Gene Polymorphisms with the Risk of Ritodrine-Induced Adverse Events in Korean Women with Preterm Labor: A Cohort Study.  Pharmaceutics. 2022, v.14 no.6, 1220. 
•  Analysis of the Impact of the Presence of Phylum Cyanobacteria in the Microbiome of Patients with Breast Cancer on Their Prognosis.  Journal of Clinical Medicine. 2022, v.11 no.24, 7272. 
•  A COVID-19 mortality prediction model for Korean patients using nationwide Korean disease control and prevention agency database.  Scientific Reports. 2022, v.12 no.1, 3311. 
•  Lipidomic Analysis of Cervicovaginal Fluid for Elucidating Prognostic Biomarkers and Relevant Phospholipid and Sphingolipid Pathways in Preterm Birth.  METABOLITES. 2023, v.13 no.2, 177. 
•  Association of paternal cadmium and other heavy metal exposure to birth outcomes using propensity score matching.  Chemosphere. 2023, v.311, 136792. 

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