학력 및 경력사항

• 이화여자대학교 의과대학 수료

• 현재  |  대한 소아과 학회, 주산의학회, 신생아학회 정회원
• 현재  | 이대부속 목동병원 소아과 교수
• 2015-2017  | 이화여자대학교 의료원 기획조정실장
• 2015-현재  | 이화여자대학교 의료원 기획조정실장
• 2013-2015  | 이대목동병원 NICU실장
• 2011-2013  | 이대목동병원 의무부장
• 2009-2011  | 이대목동병원 적정진료센터장
• 2009  | 한국의료 QA 학회 이사
• 2004  |  대한 주산의학회 간행, 정보통신 위원
• 2003-2004  | 대한 주산의학회 이사
• 2002-현재  | 대한 신생아학회 간행위원
• 2001-2002  | University of Iowa, Pediatric Depatment
• 2001  | 이대부속 목동병원 소아과 부교수
• 1999-2001  | 대한 신생아학회 총무 위원
• 1997  | 이대부속 목동병원 소아과 조교수
• 1993  | 이대부속 목동병원 소아과 전임강사
• 1992  | 이대부속병원 신생아학 전임의사로 재직 및 연세대학교 부속 세브란스병원 소아과 유전학아분과 연구강사
• 1992  | 소아과전문의 자격증 취득
• 1992  | 이대부속병원 레지던트 과정 수료
• 1989  | 이대부속병원 인턴과정 수료
• 선천성 기형의 유전적 원인 연구 및 극소체중 미숙아치료

• 2013  | GSK 우수 초록상, 대한소아과 추계학술대회
• 2007  | 2007년도 매일 진암 학술상 해외논문 부문 대한신생아학회
• 2002  | 대한 주산의학회 추계 학술 대회 우수논문 학술상

•  Mesenchymal Stem Cell-Derived Exosomes Attenuate TLR7-Mediated Mast Cell Activation.  Tissue Engineering and Regenerative Medicine. 2022, v.19 no.1, 117-129. 
•  Procollagen C-Endopeptidase Enhancer 2 Secreted by Tonsil-Derived Mesenchymal Stem Cells Increases the Oxidative Burst of Promyelocytic HL-60 Cells.  BIOLOGY-BASEL. 2022, v.11 no.2, 255. 
•  Promotion of Platelet Production by Co-Transplantation of Mesenchymal Stem Cells in Bone Marrow Transplantation.  Tissue Engineering and Regenerative Medicine. 2022, v.19 no.1, 131-139. 
•  Mesenchymal Stem Cell-Derived Exosomes Protect Muscle Loss by miR-145-5p Activity Targeting Activin A Receptors.  CELLS. 2021, v.10 no.8, 2169 SCIE Scopus dColl.. 
•  Tonsil-derived mesenchymal stem cells enhance allogeneic bone marrow engraftment via collagen IV degradation.  Stem Cell Research and Therapy. 2021, v.12 no.1, 329. 
•  A Novel Method to Differentiate Tonsil-Derived Mesenchymal Stem Cells In Vitro into Estrogen-Secreting Cells.  Tissue Engineering and Regenerative Medicine. 2020, v.18 no.2, 0. 
•  Co-transplantation of tonsil-derived mesenchymal stromal cells in bone marrow transplantation promotes thymus regeneration and T cell diversity following cytotoxic conditioning.  INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2020 , 1166-1174. 
•  Conditioned medium from human palatine tonsil mesenchymal stem cells attenuates acute graft-vs.-host disease in mice.  Molecular Medicine Reports. 2019, v.19 no.1, 609-616. 
•  Identification of WNT16 as a Predictable Biomarker for Accelerated Osteogenic Differentiation of Tonsil-Derived Mesenchymal Stem Cells In Vitro.  STEM CELLS INTERNATIONAL. 2019, v.2019, 8503148. 
•  Inhibiting Sphingosine Kinase 2 Derived-sphingosine-1-phosphate Ameliorates Psoriasis-like Skin Disease via Blocking Th17 Differentiation of Naive CD4 T Lymphocytes in Mice.  ACTA DERMATO-VENEREOLOGICA. 2019, v.99 no.6, 594-601. 
•  Tonsil-derived stem cells as a new source of adult stem cells.  WORLD JOURNAL OF STEM CELLS. 2019, v.11 no.8, 506-518. 
•  Differentiation between incomplete kawasaki disease and secondary hemophagocytic lymphohistiocytosis following kawasaki disease using n-terminal pro-brain natriuretic peptide.  Korean Journal of Pediatrics. 2018, v.61 no.5, 167-173. 
•  Tonsil-derived mesenchymal stem cell-embedded in situ crosslinkable gelatin hydrogel therapy recovers postmenopausal osteoporosis through bone regeneration.  PLOS ONE, 2018. v.13 no.7, e0200111. 
•  onsil-derived mesenchymal stem cells (T-MSCs) prevent Th17-mediated autoimmune response via regulation of the programmed death-1/programmed death ligand-1 (PD-1/PD-L1) pathway.  JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE. 2018, v.12 no.2, E1022-E1033. 
•  Conditioned media from human palatine tonsil mesenchymal stem cells regulates the interaction between myotubes and fibroblasts by IL-1Ra activity.  Journal of Cellular and Molecular Medicine. 2017, v.21 no.1, 130-141. 
•  Conditioned medium from tonsil-derived mesenchymal stem cells promotes adiponectin production.  Molecular Medicine Reports. 2017, v.16 no.5, 6170-6177. 
•  Mesenchymal stem cells ameliorate B-cell-mediated immune responses and increase IL-10-expressing regulatory B cells in an EBI3-dependent manner.  Cellular and Molecular Immunology. 2017, v.14 no.11, 895-908. 
•  Mesenchymal stem cells inhibit RANK-RANKL interactions between osteoclasts and Th17 cells via osteoprotegerin activity.  ONCOTARGET. 2017, v.8 no.48, 83419-83431. 
•  Poly I:C primes the suppressive function of human palatine tonsil-derived MSCs against Th17 differentiation by increasing PD-L1 expression.  Immunobiology. 2017, v.222 no.2, 394-398. 
•  RNA sequencing reveals a transcriptomic portrait of human mesenchymal stem cells from bone marrow, adipose tissue, and palatine tonsils.  Scientific Reports. 2017, v.7 no.1. 
•  Bioreducible Cationic Poly(amido amine)s for Enhanced Gene Delivery and Osteogenic Differentiation of Tonsil-Derived Mesenchymal Stem Cells.  JOURNAL OF BIOMEDICAL NANOTECHNOLOGY. 2016, v.12 no.5, 1023-1034. 
•  Human tonsil-derived mesenchymal stromal cells enhanced myelopoiesis in a mouse model of allogeneic bone marrow transplantation.  MOLECULAR MEDICINE REPORTS. 2016, v.14 no.4, 3045-3051. 
•  Improved Outcome of a Reduced Toxicity-Fludarabine, Cyclophosphamide, plus Antithymocyte Globulin Conditioning Regimen for Unrelated Donor Transplantation in Severe Aplastic Anemia: Comparison of 2 Multicenter Prospective Studies.  Biology of Blood and Marrow Transplantation. 2016, v.22 no.8. 
•  Myogenic differentiation potential of human tonsil-derived mesenchymal stem cells and their potential for use to promote skeletal muscle regeneration.  INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2016, v.37 no.5, 1209-1220. 
•  Tonsil-Derived Mesenchymal Stem Cells Differentiate into a Schwann Cell Phenotype and Promote Peripheral Nerve Regeneration.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2016, v.17 no.11. 
•  Tonsil-Derived Mesenchymal Stem Cells Promote Bone Mineralization and Reduce Marrow and Visceral Adiposity in a Mouse Model of Senile Osteoporosis.  STEM CELLS AND DEVELOPMENT. 2016, v.25 no.15, 1161-1171. 
•  CCN1 Secreted by Tonsil-Derived Mesenchymal Stem Cells Promotes Endothelial Cell Angiogenesis via Integrin alpha(v)beta(3) and AMPK.  JOURNAL OF CELLULAR PHYSIOLOGY. 2015, v.230 no.1, 140-149. 
•  Characterisation of insulin-producing cells differentiated from tonsil derived mesenchymal stem cells.  Differentiation. 2015, 29 SEP 2015. 
•  Clinical features, genetics, and outcome of pediatric patients with hemophagocytic lymphohistiocytosis in Korea: report of a nationwide survey from Korea Histiocytosis Working Party.  EUROPEAN JOURNAL OF HAEMATOLOGY. 2015, v.94 no.1, 51-59. 
•  Differentiated tonsil-derived mesenchymal stem cells embedded in Matrigel restore parathyroid cell functions in rats with parathyroidectomy.  Biomaterials. 2015, v.65, 140-152. 
•  Immune Suppressive Effects of Tonsil-Derived Mesenchymal Stem Cells on Mouse Bone-Marrow-Derived Dendritic Cells.  STEM CELLS INTERNATIONAL. 2015, v.2015. 
•  KMT2A (MLL)-MLLT1 rearrangement in blastic plasmacytoid dendritic cell neoplasm.  Cancer Genetics. 2015, v.208 no.9, 464-467. 
•  Tonsil-derived Mesenchymal Stem Cells Ameliorate CCl4-induced Liver Fibrosis in Mice via Autophagy Activation.  SCIENTIFIC REPORTS. 2015, v.5. 
•  Tonsil-derived mesenchymal stromal cells produce CXCR2-binding chemokines and acquire follicular dendritic cell-like phenotypes under TLR3 stimulation.  CYTOKINE. 2015, v.73 no.2, 225-235. 
•  Indoor total volatile organic compounds exposure at 6 months and atopic dermatitis prevalence at 3 years in children..  Pediatr Allergy Immunol. 2015 . 
•  The preventive effect of breast-feeding for longer than 6 months on early pubertal development among children aged 7?9 years in Korea..  Public Health Nutrition. 2015. 
•  The relationship between eosinophilia and bronchopulmonary dysplasia in premature infants at less than 34 weeks’ gestation..  Korean J Pediatr. 2014. 
•  Association of mid-pregnancy antioxidative vitamins and oxidative stress levels with infant growth during the first three years of life..  Food and Nutrition Research. 2014 . 
•  Early aggressive nutrition enhances language development in very low birth weight infants. .  Pediatr Int.. 2014. 
•  Association of Adiponectin Gene Polymorphism With Birth Weight in Korean Neonates. .  Human Genetics. 2013. 
•  Mendelian randomization analysis of the effect of maternal homocysteine during pregnancy, as represented by maternal MTFHR C677T genotype, on birth weight..  J Epidemiol. 2013. 
•  Association of vitamin D concentrations with adiposity indices among preadolescent children in Korea..  J Pediatr Endocrinol Metab.. 2013. 
•  Effect of Urinary Bisphenol A on Androgenic Hormones and Insulin Resistance in Preadolescent Girls: A Pilot Study from the Ewha Birth & Growth Cohort. Int. J. Environ. .  Res. Public Health. 2013. 
•  Influence of Antenatal Magnesium Sulfate Exposure on Perinatal Outcomes in VLBW Infants with Maternal Preeclampsia..  Neonatal Medicine. 2013. 
•  제대혈 Adiponectin과 IGF-I이 태아성장에 미치는 영향.  대한신생아학회지. 2008. 
•  Oxidative stress-related gene interactions with preterm delivery in Korean women, .  AJOG. 2008. 
•  34주 미만 미숙아 제대혈의 Interleukin-12 농도와 영아 천명 발생과의 관계, .  pediatrics. 2008. 
•  호흡곤란 증후군 미숙아에서의 동맥관 개존증의 약물 치료: Indomethacin과 경구용 Ibuprofen의 비교.  pediatrics. 2008. 
•  Soluble fms-like Tyrosine Kinase 1 and Placental Growth Factor in Premature Neonates of Preeclampsia Mothers..  JKMS. 2008 . 
•  Effects of probiotics on enteric flora and feeding tolerance in preterm infants, .  Neonate. 2007. 
•  Successful treatment with Total Parenteral Nutrition fluid extravasation injuries In preterm,.  JKMS. 2007. 
•  Association of antioxidant vitamins and oxidative stress levels in pregnancy with infants growth during the first year of life,.  Nutrition. 2007. 

• 소아과학 개정 8판 (2004년 1월 발간)

  |