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순환기내과, 심장혈관센터 관심의료진 등록

전문 진료 분야

관상동맥 중재시술, 말초혈관질환 중재시술, 선천성 기형 및 구조심장질환의 중재시술, 판막질환 및 심부전증의 중재시술, 고혈압(만16세이상), 코로나 후유증 클리닉

진료 일정

진료예약 간편 예약 고맙습니다

학력 및 경력사항

학력사항

  • 연세대학교 의과대학 대학원 박사
  • 연세대학교 의과대학 대학원 석사
  • 연세대학교 의과대학 졸업

교육 및 연구경력

  • 심혈관질환연구센터장
  • 이화여자대학교 의학과 교수
  • 연세의료원 연구강사
  • 연세의료원 내과 수련의

기타 학술 관련 경력

  • 2009-2010  |  The Wallace H. Coulter Dept. of Biomedical Engineering at Georgia Tech and Emory University, Visiting Professor
  • 대한심혈관중재시술학회 연구위원
  • 바이오/의료영상연구소 소장

논문

  •  A randomized, double-blind, multicenter, phase III study on the efficacy and safety of a combination treatment involving fimasartan, amlodipine, rosuvastatin in patients with essential hypertension and dyslipidemia who fail to respond adequately to fimasartan monotherapy.  Clinical Hypertension. 2022, v.28 no.1, 40. 
  •  Efficacy and Safety of SID142 in Patients With Peripheral Arterial Disease: A Multicenter, Randomized, Double-Blind, Active-Controlled, Parallel-Group, Phase III Clinical Trial.  Clinical Therapeutics. 2022, v.44 no.4, 508-528. 
  •  Fluid Shear Stress Regulates the Landscape of microRNAs in Endothelial Cell-Derived Small Extracellular Vesicles and Modulates the Function of Endothelial Cells.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022, v.23 no.3, 1314. 
  •  Potential application of biomimetic exosomes in cardiovascular disease: focused on ischemic heart disease.  BMB REPORTS. 2022, v.55 no.1, 30-38. 
  •  Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Protect Cardiomyocytes from Doxorubicin-Induced Cardiomyopathy by Upregulating Survivin Expression via the miR-199a-3p-Akt-Sp1/p53 Signaling Pathway.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021, v.22 no.13, 7102. 
  •  Clinical impact of pre-hypertension on the risk of cancer in male and female subjects.  Scientific Reports. 2020, v.10 no.1, 9974. 
  •  Efficacy and safety of co-administered telmisartan/amlodipine and rosuvastatin in subjects with hypertension and dyslipidemia.  Journal of Clinical Hypertension. 2020, v.22 no.10, 1835-1845. 
  •  Safety and Efficacy of a New Ultrathin Sirolimus-Eluting Stent with Abluminal Biodegradable Polymer in Real-World Practice.  KOREAN CIRCULATION JOURNAL. 2020, v.50 no.4, 317-327. 
  •  Validation of the diagnostic performance of 'HeartMedi V.1.0', a novel CT-derived fractional flow reserve measurement, for patients with coronary artery disease: a study protocol.  BMJ open. 2020, v.10 no.7, e037780. 
  •  Coxsackievirus and adenovirus receptor mediates the responses of endothelial cells to fluid shear stress.  Experimental and Molecular Medicine. 2019, v.51, 144. 
  •  Extracorporeal shock waves protect cardiomyocytes from doxorubicin-induced cardiomyopathy by upregulating survivin via the integrin-ILK-Akt-Sp1/p53 axis.  Scientific Reports. 2019, v.9 no.1, 12149. 
  •  Blood flow characteristics of diabetic patients with complications detected by optical measurement.  BioMedical Engineering Online. 2018, v.17 no.1. 
  •  Fluid shear stress regulates the expression of Lectin-like oxidized low density lipoprotein receptor-1 via KLF2-AP-1 pathway depending on its intensity and pattern in endothelial cells.  Atherosclerosis. 2018, v.270, 76-88. 
  •  Prognostic implications of late gadolinium enhancement at the right ventricular insertion point in patients with non-ischemic dilated cardiomyopathy: A multicenter retrospective cohort study.  PLOS ONE. 2018, v.13 no.11, e0208100. 
  •  Urinary Exosomal and cell-free DNA Detects Somatic Mutation and Copy Number Alteration in Urothelial Carcinoma of Bladder.  Scientific Reports. 2018, v.8 no.1, 14707. 
  •  Clinical implication of an impaired fasting glucose and prehypertension related to new onset atrial fibrillation in a healthy Asian population without underlying disease: A nationwide cohort study in Korea.  European Heart Journal. 2017, v.38 no.34, 2599-2607. 
  •  Extracellular matrix-derived extracellular vesicles promote cardiomyocyte growth and electrical activity in engineered cardiac atria.  Biomaterials. 2017, v.146, 49-59. 
  •  Selective tubular activation of hypoxia-inducible factor-2α has dual effects on renal fibrosis.  Scientific Reports. 2017, v.7 no.1. 
  •  Discovery of novel peptides targeting pro-atherogenic endothelium in disturbed flow regions-Targeted siRNA delivery to pro-atherogenic endothelium in vivo.  Scientific Reports. 2016, v.6. 
  •  Ursodeoxycholic Acid (UDCA) exerts anti-Atherogenic effects by inhibiting RAGE signaling in diabetic atherosclerosis.  PLoS ONE. 2016, v.11 no.1. 
  •  Csk-Induced Phosphorylation of Src at Tyrosine 530 is Essential for H2O2-Mediated Suppression of ERK1/2 in Human Umbilical Vein Endothelial Cells.  SCIENTIFIC REPORTS. 2015, v.5. 
  •  Novel mechanism of gene transfection by low-energy shock wave.  SCIENTIFIC REPORTS. 2015, v.5. 
  •  Ursodeoxycholic Acid (UDCA) Exerts Anti-Atherogenic Effects by Inhibiting Endoplasmic Reticulum (ER) Stress Induced by Disturbed Flow.  MOLECULES AND CELLS. 2015, v.38 no.10, 851-858. 
  •  Vascular Proteomics Reveal Novel Proteins Involved in SMC Phenotypic Change: OLR1 as a SMC Receptor Regulating Proliferation and Inflammatory Response.  PLOS ONE. 2015, v.10 no.8. 
  •  Effect of anemia correction on left ventricular structure and filling pressure in anemic patients without overt heart disease.  KOREAN JOURNAL OF INTERNAL MEDICINE. 2014, v.29, 445-453.